I am fascinated by the similarities between artificial neural networks and biological neural networks, and I am particularly interested in how machine learning algorithms and the brain are solving the complex task of vision. To gain insight into these matters, I am using deep neural networks to model the early visual cortex of monkeys and mice, to see in which cases these models work, and in which cases they do not. Using network dissection techniques and in silico experiments, my aim is to discover functional principles of artificial neural networks that are instructive for neuroscientific experiments, and that could lead to insights into the fundamentals of our cognitive system and its implementation. I am also passionate about open science, sharing of data and methods, and the movement of using AI to empower society.
Lab members are shown in this color.
2024
Polina Turishcheva, Paul G. Fahey, Michaela Vystrčilová, Laura Hansel, Rachel E Froebe, Kayla Ponder, Yongrong Qiu, Konstantin Friedrich Willeke, Mohammad Bashiri, Ruslan Baikulov, Yu Zhu, Lei Ma, Shan Yu, Tiejun Huang, Bryan M. Li, Wolf De Wulf, Nina Kudryashova, Matthias H. Hennig, Nathalie Rochefort, Arno Onken, Eric Wang, Zhiwei Ding, Andreas S. Tolias, Fabian H. Sinz, Alexander S Ecker
Retrospective for the Dynamic Sensorium Competition for predicting large-scale mouse primary visual cortex activity from videos
NeurIPS 2024
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Taesung Jung, Nanyu Zeng, Jason D. Fabbri, Guy Eichler, Zhe Li, Konstantin Willeke, Katie E. Wingel, Agrita Dubey, Rizwan Huq, Mohit Sharma, Yaoxing Hu, Girish Ramakrishnan, Kevin Tien, Paolo Mantovani, Abhinav Parihar, Heyu Yin, Denise Oswalt, Alexander Misdorp, Ilke Uguz, Tori Shinn, Gabrielle J. Rodriguez, Cate Nealley, Ian Gonzales, Michael Roukes, Jeffrey Knecht, Daniel Yoshor, Peter Canoll, Eleonora Spinazzi, Luca P. Carloni, Bijan Pesaran, Saumil Patel, Brett Youngerman, R. James Cotton, Andreas Tolias, Kenneth L. Shepard
Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface device
bioRxiv
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Jiakun Fu, Suhas Shrinivasan, Luca Baroni, Zhuokun Ding, Paul G. Fahey, Paweł Pierzchlewicz, Kayla Ponder, Rachel Froebe, Lydia Ntanavara, Taliah Muhammad, Konstantin F Willeke, Eric Wang, Zhiwei Ding, Dat T. Tran, Stelios Papadopoulos, Saumil Patel, Jacob Reimer, Alexander S. Ecker, Xaq Pitkow, Jan Antolik, Fabian H. Sinz, Ralf M. Haefner, Andreas S. Tolias, Katrin Franke
Pattern completion and disruption characterize contextual modulation in the visual cortex
bioRxiv
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Jiakun Fu, Pawel A. Pierzchlewicz, Konstantin F. Willeke, Mohammad Bashiri, Taliah Muhammad, Maria Diamantaki, Emmanouil Froudarakis, Kelli Restivo, Kayla Ponder, George H. Denfield, Fabian H. Sinz, Andreas S. Tolias, Katrin Franke
Heterogeneous orientation tuning in primary visual cortex of mice diverges from Gabor-like receptive fields in primates
Cell Reports
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Santiago A. Cadena, Konstantin F. Willeke, Kelli Restivo, George Denfield, Fabian H. Sinz, Matthias Bethge, Andreas S. Tolias, Alexander S. Ecker
Diverse task-driven modeling of macaque V4 reveals functional specialization towards semantic tasks
PLoS Computational Biology
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2023
Max F. Burg, Thomas Zenkel, Michaela Vystrčilová, Jonathan Oesterle, Larissa Höfling, Konstantin F. Willeke, Jan Lause, Sarah Müller, Paul G. Fahey, Zhiwei Ding, Kelli Restivo, Shashwat Sridhar, Tim Gollisch, Philipp Berens, Andreas S. Tolias, Thomas Euler, Matthias Bethge, Alexander S. Ecker
Most discriminative stimuli for functional cell type identification
arXiv
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Pawel A. Pierzchlewicz, Konstantin F. Willeke, Arne F. Nix, Pavithra Elumalai, Kelli Restivo, Tori Shinn, Cate Nealley, Gabrielle Rodriguez, Saumil Patel, Katrin Franke, Andreas S. Tolias, Fabian H. Sinz
Energy Guided Diffusion for Generating Neurally Exciting Images
NeurIPS
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Konstantin F. Willeke, Paul G. Fahey, Mohammad Bashiri, Laura Hansel, Christoph Blessing, Konstantin-Klemens Lurz, Max F. Burg, Santiago A. Cadena, Zhiwei Ding, Kayla Ponder, Taliah Muhammad, Saumil S. Patel, Kaiwen Deng, Yuanfang Guan, Yiqin Zhu, Kaiwen Xiao, Xiao Han, Simone Azeglio, Ulisse Ferrari, Peter Neri, Olivier Marre, Adrian Hoffmann, Kirill Fedyanin, Kirill Vishniakov, Maxim Panov, Subash Prakash, Kishan Naik, Kantharaju Narayanappa, Alexander S. Ecker, Andreas S. Tolias, Fabian H. Sinz
Retrospective on the SENSORIUM 2022 competition
Proceedings of Machine Learning Research
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Polina Turishcheva, Paul G. Fahey, Laura Hansel, Rachel Froebe, Kayla Ponder, Michaela Vystrčilová, Konstantin F. Willeke, Mohammad Bashiri, Eric Wang, Zhiwei Ding, Andreas S. Tolias, Fabian H. Sinz, Alexander S. Ecker
The Dynamic Sensorium competition for predicting large-scale mouse visual cortex activity from videos
arXiv
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Konstantin F. Willeke1, Kelli Restivo1, Katrin Franke, Arne F. Nix, Santiago A. Cadena, Tori Shinn, Cate Nealley, Gabby Rodriguez, Saumil Patel, Alexander S. Ecker, Fabian H. Sinz2, Andreas S. Tolias2
Deep learning-driven characterization of single cell tuning in primate visual area V4 unveils topological organization
bioRxiv
, equal contribution: 1, 2
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2022
Luca Baroni1, Mohammad Bashiri1, Konstantin Friedrich Willeke, Ján Antolík, Fabian Sinz
Learning Invariance Manifolds of Visual Sensory Neurons
Neurips 2022 Workshop NeurReps
, equal contribution: 1
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Katrin Franke1, Konstantin F. Willeke1, Kayla Ponder, Mario Galdamez, Taliah Muhammad, Saumil Patel, Emmanouil Froudarakis, Jacob Reimer, Fabian H. Sinz, Andreas S. Tolias
State-dependent pupil dilation rapidly shifts visual feature selectivity
Nature
, equal contribution: 1
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Konstantin F. Willeke, Paul G. Fahey, Mohammad Bashiri, Laura Pede, Max F. Burg, Christoph Blessing, Santiago A. Cadena, Zhiwei Ding, Konstantin-Klemens Lurz, Kayla Ponder, Taliah Muhammad, Saumil S. Patel, Alexander S. Ecker, Andreas S. Tolias, Fabian H. Sinz
The Sensorium competition on predicting large-scale mouse primary visual cortex activity
arXiv
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2021
Shahd Safarani, Arne Nix, Konstantin Willeke, Santiago A. Cadena, Kelli Restivo, George Denfield, Andreas S. Tolias, Fabian H. Sinz
Towards robust vision by multi-task learning on monkey visual cortex
NeurIPS (accepted)
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Shahd Safarani, Arne Nix, Konstantin Willeke, Santiago A. Cadena, Kelli Restivo, George Denfield, Andreas S. Tolias, Fabian H. Sinz
Towards robust vision by multi-task learning on monkey visual cortex
ICLR 2021 Workshop: How Can Findings About The Brain Improve AI Systems?
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Konstantin-Klemens Lurz, Mohammad Bashiri, Konstantin Friedrich Willeke, Akshay Kumar Jagadish, Eric Wang, Edgar Y Walker, Santiago Cadena, Taliah Muhammad, Eric Cobos, Andreas Tolias, Alexander Ecker, Fabian Sinz
Generalization in data-driven models of primary visual cortex
ICLR (spotlight)
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